Early detection of cystic fibrosis lung disease: multiple breath washout vs. raised volume tests
نویسندگان
چکیده
Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL, Institute of Child Health, London. Department of Pediatric Clinical Physiology, Queen Silvia Children’s Hospital, Göteborg, Sweden. Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London. Department of Child Health, Royal London Hospital, London. Department of Paediatric Respiratory Medicine, Great Ormond Street Hospital for Children NHS Trust, London. Department of Child Health, King’s College Hospital, London. Department of Child Health, University Hospital Lewisham, London. Centre for Paediatric Epidemiology and Biostatistics, UCL, Institute of Child Health, London.
منابع مشابه
Early detection of cystic fibrosis lung disease: multiple-breath washout versus raised volume tests.
BACKGROUND Lung clearance index (LCI), a measure of ventilation inhomogeneity derived from the multiple-breath inert gas washout (MBW) technique, has been shown to detect abnormal lung function more readily than spirometry in preschool children with cystic fibrosis, but whether this holds true during infancy is unknown. OBJECTIVES To compare the extent to which parameters derived from the MBW...
متن کاملCYSTIC FIBROSIS Early detection of cystic fibrosis lung disease: multiple-breath washout versus raised volume tests
Sooky Lum, Per Gustafsson, Henrik Ljungberg, Georg Hülskamp, Andrew Bush, Siobhán B Carr, Rosemary Castle, Ah-fong Hoo, John Price, Sarath Ranganathan, John Stroobant, Angie Wade, Colin Wallis, Hilary Wyatt, Janet Stocks on behalf of the London Cystic Fibrosis Collaboration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
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I nert gas washout tests including single breath washout (SBW) and multiple breath washout (MBW) have been used for several decades across a wide age range spanning from early infancy to late adulthood. In the past, these lung function tests were typically applied in research settings, assessing lung volume and ventilation distribution in order to gain insight into presence, severity and progre...
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